You’ve got plans tonight. Maybe it’s your mate’s birthday, maybe it’s a night at the pub after a tough week, or maybe you just fancy hitting the town. Whatever the reason, the big question always lingers in the back of your mind: how bad is this going to feel tomorrow morning?
That’s where smart supplementation comes in. No, nothing’s going to magically erase the effects of alcohol—let’s be clear, you can’t “out-supplement” a tequila binge—but the right strategy can reduce the damage, support your body while you drink, and speed up recovery so you don’t lose your entire Sunday to the sofa.
Here’s the full breakdown of which supplements are worth taking before a night out, why they matter, and how to use them.
Do Supplements Actually Help Before Drinking?
Here’s the truth: your body sees alcohol as a toxin. The liver prioritises clearing it above everything else. That means digestion slows, nutrient absorption drops, and hydration nosedives.
Taking supplements before drinking isn’t about eliminating alcohol’s effects—it’s about giving your body back-up reserves. Think of it as pre-loading your system with the nutrients and hydration you’re about to deplete.
Done right, it means:
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Less brutal hangovers
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Better hydration balance
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Faster liver detox
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Less next-day anxiety and fatigue
And yes—science backs this. Magnesium, B vitamins, and electrolytes have all been studied for their ability to support recovery after alcohol.
What Should I Take Before Drinking Alcohol to Prevent a Hangover?
The foundation of a “pre-night out” stack looks like this:
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Electrolytes → Sodium, potassium, and magnesium keep hydration in check. Alcohol is a diuretic, meaning you’ll lose fluid fast.
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Multivitamin (with B-complex + zinc) → B vitamins are key to energy production and liver function, while zinc supports detox. Alcohol depletes both.
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Magnesium → Reduces stress, relaxes muscles, and helps regulate sleep—big bonus after a night of stimulation and booze.
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Omega-3s → Anti-inflammatory, supporting brain health while alcohol temporarily inflames the nervous system.
👉 That’s why The Ten Percent Club Electrolyte Drink Mix, Applied Nutrition Multivitamin, BetterYou Magnesium Water, and Supplement Needs Omega 3 make the perfect base here.
Do Hangover-Prevention Pills Actually Work?
Let’s address the elephant in the room: all those trendy “hangover prevention” pills you see on Instagram. Most of them are overpriced blends of electrolytes, vitamins, and herbs—basically the same nutrients we’re already talking about, just in a capsule and with a flashy name.
While some may help, you don’t need gimmicks. A quality multivitamin, proper electrolytes, and targeted nutrients like magnesium will outperform most of those so-called miracle pills.
Which Vitamins Are Best Before a Night Out?
If you’re going to focus on just a few vitamins, make it these:
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B-Complex (especially B12 & B6): Supports the liver’s breakdown of alcohol, reduces fatigue, and helps fight “hangxiety.”
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Vitamin C: Powerful antioxidant—alcohol increases oxidative stress, and vitamin C helps blunt the damage.
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Vitamin D: Most of us are deficient anyway, and it helps regulate mood and immunity, both of which take a hit after drinking.
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Zinc: Crucial for liver enzyme function and recovery.
👉 Instead of buying them all separately, a comprehensive multivitamin like Applied Nutrition Multivitamin keeps things simple.
Does Magnesium Prevent or Reduce Hangovers?
This is a big one. Alcohol messes with magnesium levels by increasing urinary excretion. That’s why after a heavy night you often feel restless, anxious, or crampy—those are signs of low magnesium.
Taking magnesium before drinking can:
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Reduce muscle tension
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Support calmness
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Help you sleep more deeply (even if alcohol usually disrupts sleep cycles)
That’s where BetterYou Magnesium Water fits in. It’s hydrating, simple to sip, and delivers exactly what you’ll lose later in the night.
Do Electrolytes Help with Hangovers?
Without question—yes. Electrolytes are probably the most underrated hangover hack out there. Here’s why:
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Alcohol is a diuretic → dehydration = headaches + fatigue
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Loss of sodium + potassium = dizziness, weakness
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Electrolytes restore balance, prevent the “cotton mouth + shaky hands” combo the next morning
The trick is to take them before and during the night, not just the next morning. Knock back a sachet of The Ten Percent Club Electrolyte Drink Mix with water before heading out, and maybe even carry another to have when you get home.
Which Supplements Protect the Liver When You Drink Alcohol?
Your liver is the MVP tonight. While NAC and milk thistle are often talked about, you don’t need to overcomplicate things. Focus on these essentials:
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B vitamins → key for liver enzyme activity
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Omega-3s → reduce inflammation and protect liver cells
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Zinc → supports detoxification pathways
That’s why Supplement Needs Omega 3 works perfectly here, giving your liver some backup while you party.
Does Creatine Make Hangovers Worse?
Funny enough, creatine isn’t part of the “classic hangover prevention” lineup, but it deserves a mention. It won’t worsen hangovers, and it may actually help protect your muscles and energy stores during recovery.
Think about it: you still want to train the next day, right? While alcohol depletes your recovery capacity, keeping Naughty Boy Prime Creatine in your routine means you don’t set your gym progress back every time you have a night out.
What to Expect in Part 2
So far, we’ve laid the foundation: electrolytes, multivitamins, magnesium, omega-3, and creatine all play their roles in supporting your body before and during a night out.
But in Part 2, we’ll go deeper:
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The timing strategy (when exactly to take each supplement)
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Whether you should take B12 before or after drinking
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How to stack electrolytes with other nutrients for maximum effect
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The supplements that help your body metabolise alcohol faster
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The truth about vitamin C as a hangover cure
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And finally—what actually works the morning after
What Supplements Should You Take Before a Night Out? (Part 2)
In Part 1, we broke down the essentials—electrolytes, multivitamins, magnesium, omega-3s, and creatine—and why they matter before a night out. Now let’s get practical: when to take them, how to stack them, and what to do the morning after.
This is where we move from “theory” to an actual game plan you can follow.
Should I Take B12 Before or After Drinking?
Vitamin B12 is one of the most important nutrients when it comes to drinking. Alcohol depletes B12 rapidly, and low levels are linked to fatigue, anxiety, and brain fog the next morning.
So when’s the best time to take it?
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Before drinking: Preloads your system and supports liver enzymes as alcohol is processed.
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After drinking: Helps restore what’s been depleted, supporting energy production and nervous system function.
👉 The smart move? Both. That’s why a well-rounded multivitamin like Applied Nutrition Multivitamin works perfectly—take one before heading out and another the morning after.
How to Time Your Pre-Night Out Stack
Timing matters almost as much as the supplements themselves. Here’s a simple schedule:
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1–2 hours before going out:
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The Ten Percent Club Electrolyte Drink Mix → locks in hydration and minerals.
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Applied Nutrition Multivitamin → provides B vitamins, zinc, and vitamin C upfront.
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BetterYou Magnesium Water → supports calmness and pre-sleep recovery.
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The Ten Percent Club Electrolyte Drink Mix → locks in hydration and minerals.
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During the night (optional):
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Another electrolyte sachet if you’re pacing drinks with water.
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Another electrolyte sachet if you’re pacing drinks with water.
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When you get home:
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A second serving of electrolytes.
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Supplement Needs Omega 3 → reduce inflammation while you sleep.
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A second serving of electrolytes.
This approach means your body always has the raw materials it needs to deal with the stress alcohol brings.
Which Vitamins or Supplements Help Your Body Metabolise Alcohol Faster?
The body metabolises alcohol primarily via the liver, using enzymes that depend on specific nutrients:
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B vitamins (B1, B6, B12): Support alcohol dehydrogenase enzymes.
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Zinc: Helps break down acetaldehyde (the toxic byproduct of alcohol).
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Vitamin C: Antioxidant defence during oxidative stress from drinking.
While nothing makes alcohol vanish instantly, these nutrients support faster, cleaner processing, leaving fewer toxic byproducts hanging around to make you feel terrible.
👉 This is exactly why Applied Nutrition Multivitamin does heavy lifting here—it’s a one-stop way of feeding your liver the tools it needs.
Does Magnesium Prevent or Reduce Hangovers (and Can You Take It With Alcohol)?
Magnesium is a quiet hero here. Beyond its calming effects, it helps regulate neurotransmitters like GABA, which alcohol initially boosts but then crashes. Low GABA = restless sleep and racing thoughts.
Taking BetterYou Magnesium Water before drinking creates a protective buffer, and yes, you can sip it alongside alcohol. It won’t cause interactions—it just replaces what you’re losing.
Do Electrolytes Work Better Before or After Drinking?
The answer: both.
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Before: They set your hydration baseline. Go into the night already low, and you’ll crash fast.
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After: They replenish what’s been lost during your drinking session.
👉 For best results: one sachet of The Ten Percent Club Electrolyte Drink Mix before heading out, another when you get home.
What Supplements Protect the Liver When You Drink?
Your liver is working overtime, so give it support. Supplements that help include:
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NAC (N-Acetyl Cysteine): Often used for glutathione production, a master antioxidant.
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Milk Thistle: Traditional herbal liver support.
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Omega-3s: Scientifically backed to reduce inflammation and protect liver cells.
While NAC and milk thistle are great extras, your daily baseline of Supplement Needs Omega 3 is the most practical and sustainable.
Does Vitamin C Help a Hangover?
Vitamin C won’t magically erase a hangover, but it’s a powerful antioxidant that reduces oxidative stress alcohol leaves behind. Paired with electrolytes, it can help reduce headaches and fatigue.
This is another area where Applied Nutrition Multivitamin steps in—it ensures you’re getting enough vitamin C without needing a separate supplement.
What Is the Best Hangover Cure the Morning After?
The honest truth? There’s no silver bullet. But combining these things sets you up for the best recovery possible:
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Electrolytes → Fix hydration first.
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Multivitamin → Replace vitamins lost during drinking.
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Magnesium → Calm nerves and restore mineral balance.
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Protein + carbs → Help stabilise blood sugar.
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Creatine → Keep your gym progress intact.
Instead of reaching for greasy food, Per4m Whey Hydrate is a smarter breakfast move—it delivers protein, electrolytes, and hydration in one shake.
Conclusion: Build Your Pre-Night Out Stack
Here’s the bottom line: you can’t drink like a rockstar and wake up like a saint. But with the right before-night supplementation, you can massively improve how you feel the next day.
✅ The Ten Percent Club Electrolyte Drink Mix → hydration hero
✅ Applied Nutrition Multivitamin → B-complex, zinc, vitamin C
✅ BetterYou Magnesium Water → calmness + mineral balance
✅ Supplement Needs Omega 3 → anti-inflammatory liver support
✅ Naughty Boy Prime Creatine → gym recovery insurance
✅ Per4m Whey Hydrate → next-morning reset
Think of it as investing in damage limitation—the smarter you prepare, the less your night out costs you tomorrow.
FAQ: Supplements Before a Night Out
1. What’s the number one supplement to take before drinking?
Electrolytes. They set your hydration baseline and prevent the worst hangover symptoms.
2. Do hangover prevention pills really work?
Some help, but most are just overpriced blends of vitamins and electrolytes you can get individually.
3. Is it better to take magnesium before or after drinking?
Both. Before helps protect sleep quality, after helps replenish what alcohol depletes.
4. Should I take creatine before drinking?
Creatine won’t worsen hangovers. Keeping it in your routine protects your training progress.
5. Do omega-3s help with alcohol damage?
Yes—they reduce inflammation and support liver cell health.
6. Should I take B12 before or after alcohol?
Both—one serving before to preload, one after to restore levels.
7. Can electrolytes really prevent hangovers?
They won’t stop them completely, but they massively reduce dehydration symptoms like headaches and dizziness.
8. What’s the best breakfast after a night out?
Protein + electrolytes. A shake like Per4m Whey Hydrate works better than greasy food.
9. Can supplements make me immune to hangovers?
No—alcohol still has an impact. But supplements can make the recovery much smoother.
10. Should I double my supplement doses before drinking?
No—stick to normal doses. The key is timing and consistency, not megadosing.